Human Interleukin-2 (Carrier-free)

Interleukin-2 (IL-2) is one of a family of polypeptides that mediate interactions between leukocytes. It is a T-cell growth factor. It stimulates proliferation and enhances function of other T-cells, natural killer (NK) cells and B-cells. IL-2-activated B-cells generate secretory rather than membrane-associated IgM, and macrophages gain maturity and elaborate transforming growth factor-β (TGF-β) when stimulated with IL-2.

IL-2 is a small 15.5-kDa four α-helical bundle cytokine, which has been one of the most studied cytokines since its discovery. It is produced by antigen simulated CD4+ T cells, while it can also be produced by CD8+ cells, natural killer (NK) cells, and activated dendritic cells (DC). Human IL-2 is recombinant protein optimized for use in cell culture, differentiation studies, and functional assays, and possesses the same biological properties as naturally occurring IL-2

Recombinant Interleukin-2, (hIL-2) is produced in E. coli and purified by standard chromatographic techniques.

2ug of recombinant human IL-2 resolved by SDS-PAGE reducing condition, showing a single band at 15.5 kDa.

Source

E.coli, Sterile filtered lyophilized and salt free; Purity ≥ 95% by SDS-PAGE

AA Sequence

MAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVL
NLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT

Note: MicroProtein’s products are manufactured using animal-free components and materials.

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